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The Transcription Factor ATF4 Promotes Skeletal Myofiber Atrophy during Fasting

Prolonged fasting alters skeletal muscle gene expression in a manner that promotes myofiber atrophy, but the underlying mechanisms are not fully understood. Here, we examined the potential role of activating transcription factor 4 (ATF4), a transcription factor with an evolutionarily ancient role in...

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Detalhes bibliográficos
Main Authors: Ebert, Scott M., Monteys, Alex Mas, Fox, Daniel K., Bongers, Kale S., Shields, Bridget E., Malmberg, Sharon E., Davidson, Beverly L., Suneja, Manish, Adams, Christopher M.
Formato: Artigo
Idioma:Inglês
Publicado em: The Endocrine Society 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2852358/
https://ncbi.nlm.nih.gov/pubmed/20197309
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/me.2009-0345
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