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mRNA Expression Signatures of Human Skeletal Muscle Atrophy Identify a Natural Compound that Increases Muscle Mass

Skeletal muscle atrophy is a common and debilitating condition that lacks a pharmacologic therapy. To develop a potential therapy, we identified 63 mRNAs that were regulated by fasting in both human and mouse muscle, and 29 mRNAs that were regulated by both fasting and spinal cord injury in human mu...

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Main Authors: Kunkel, Steven D., Suneja, Manish, Ebert, Scott M., Bongers, Kale S., Fox, Daniel K., Malmberg, Sharon E., Alipour, Fariborz, Shields, Richard K., Adams, Christopher M.
Formato: Artigo
Idioma:Inglês
Publicado: 2011
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3120768/
https://ncbi.nlm.nih.gov/pubmed/21641545
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cmet.2011.03.020
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