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TAZ Protein Accumulation Is Negatively Regulated by YAP Abundance in Mammalian Cells
The mammalian Hippo signaling pathway regulates cell growth and survival and is frequently dysregulated in cancer. YAP and TAZ are transcriptional coactivators that function as effectors of this signaling pathway. Aberrant YAP and TAZ activity is reported in several human cancers, and normally the e...
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| Udgivet i: | J Biol Chem |
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| Main Authors: | , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
American Society for Biochemistry and Molecular Biology
2015
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4646034/ https://ncbi.nlm.nih.gov/pubmed/26432639 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M115.692285 |
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