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TAZ Protein Accumulation Is Negatively Regulated by YAP Abundance in Mammalian Cells

The mammalian Hippo signaling pathway regulates cell growth and survival and is frequently dysregulated in cancer. YAP and TAZ are transcriptional coactivators that function as effectors of this signaling pathway. Aberrant YAP and TAZ activity is reported in several human cancers, and normally the e...

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Detaylı Bibliyografya
Yayımlandı:J Biol Chem
Asıl Yazarlar: Finch-Edmondson, Megan L., Strauss, Robyn P., Passman, Adam M., Sudol, Marius, Yeoh, George C., Callus, Bernard A.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Society for Biochemistry and Molecular Biology 2015
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4646034/
https://ncbi.nlm.nih.gov/pubmed/26432639
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M115.692285
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