Characterizing the Diverse Mutational Pathways Associated with R5-Tropic Maraviroc Resistance: HIV-1 That Uses the Drug-Bound CCR5 Coreceptor

Entry inhibitors represent a potent class of antiretroviral drugs that target a host cell protein, CCR5, an HIV-1 entry coreceptor, and not viral protein. Lack of sensitivity can occur due to preexisting virus that uses the CXCR4 coreceptor, while true resistance occurs through viral adaptation to u...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:J Virol
Egile Nagusiak: Jiang, Xiaowei, Feyertag, Felix, Meehan, Conor J., McCormack, Grace P., Travers, Simon A., Craig, Charles, Westby, Mike, Lewis, Marilyn, Robertson, David L.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Society for Microbiology 2015
Gaiak:
Genetic Diversity and Evolution
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4645647/
https://ncbi.nlm.nih.gov/pubmed/26339063
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01384-15
Etiketak: Etiketa erantsi
Etiketarik gabe, Izan zaitez lehena erregistro honi etiketa jartzen!

Antzeko izenburuak