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Regulation of RNF144A E3 Ubiquitin Ligase Activity by Self-association through Its Transmembrane Domain
RNF144A, an E3 ubiquitin ligase for DNA-dependent protein kinase catalytic subunit (DNA-PKcs), can promote DNA damage-induced cell apoptosis. Here we characterize an important regulation of RNF144A through its transmembrane (TM) domain. The TM domain of RNF144A is highly conserved among species. Del...
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| Publicado no: | J Biol Chem |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Biochemistry and Molecular Biology
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4645615/ https://ncbi.nlm.nih.gov/pubmed/26216882 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M115.645499 |
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