Maximizing the Therapeutic Potential of Hsp90 Inhibitors

Hsp90 is required for maintaining the stability and activity of a diverse group of client proteins, including protein kinases, transcription factors and steroid hormone receptors involved in cell signaling, proliferation, survival, oncogenesis and cancer progression. Inhibition of Hsp90 alters the H...

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Bibliografiset tiedot
Julkaisussa:Mol Cancer Res
Päätekijät: Butler, Lisa M., Ferraldeschi, Roberta, Armstrong, Heather K., Centenera, Margaret M., Workman, Paul
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2015
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Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC4645455/
https://ncbi.nlm.nih.gov/pubmed/26219697
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1541-7786.MCR-15-0234
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