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Maximizing the Therapeutic Potential of Hsp90 Inhibitors

Hsp90 is required for maintaining the stability and activity of a diverse group of client proteins, including protein kinases, transcription factors and steroid hormone receptors involved in cell signaling, proliferation, survival, oncogenesis and cancer progression. Inhibition of Hsp90 alters the H...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Mol Cancer Res
Egile Nagusiak: Butler, Lisa M., Ferraldeschi, Roberta, Armstrong, Heather K., Centenera, Margaret M., Workman, Paul
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2015
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4645455/
https://ncbi.nlm.nih.gov/pubmed/26219697
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1541-7786.MCR-15-0234
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