Influences on the Design and Purification of Soluble, Recombinant Native-Like HIV-1 Envelope Glycoprotein Trimers

We have investigated factors that influence the production of native-like soluble, recombinant trimers based on the env genes of two isolates of human immunodeficiency virus type 1 (HIV-1), specifically 92UG037.8 (clade A) and CZA97.012 (clade C). When the recombinant trimers based on the env genes...

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Vydáno v:J Virol
Hlavní autoři: Ringe, Rajesh P., Yasmeen, Anila, Ozorowski, Gabriel, Go, Eden P., Pritchard, Laura K., Guttman, Miklos, Ketas, Thomas A., Cottrell, Christopher A., Wilson, Ian A., Sanders, Rogier W., Cupo, Albert, Crispin, Max, Lee, Kelly K., Desaire, Heather, Ward, Andrew B., Klasse, P. J., Moore, John P.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2015
Témata:
Vaccines and Antiviral Agents
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4645310/
https://ncbi.nlm.nih.gov/pubmed/26311893
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01768-15
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