Influences on the Design and Purification of Soluble, Recombinant Native-Like HIV-1 Envelope Glycoprotein Trimers

We have investigated factors that influence the production of native-like soluble, recombinant trimers based on the env genes of two isolates of human immunodeficiency virus type 1 (HIV-1), specifically 92UG037.8 (clade A) and CZA97.012 (clade C). When the recombinant trimers based on the env genes...

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發表在:J Virol
Main Authors: Ringe, Rajesh P., Yasmeen, Anila, Ozorowski, Gabriel, Go, Eden P., Pritchard, Laura K., Guttman, Miklos, Ketas, Thomas A., Cottrell, Christopher A., Wilson, Ian A., Sanders, Rogier W., Cupo, Albert, Crispin, Max, Lee, Kelly K., Desaire, Heather, Ward, Andrew B., Klasse, P. J., Moore, John P.
格式: Artigo
語言:Inglês
出版: American Society for Microbiology 2015
主題:
Vaccines and Antiviral Agents
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC4645310/
https://ncbi.nlm.nih.gov/pubmed/26311893
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01768-15
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