Influences on the Design and Purification of Soluble, Recombinant Native-Like HIV-1 Envelope Glycoprotein Trimers

We have investigated factors that influence the production of native-like soluble, recombinant trimers based on the env genes of two isolates of human immunodeficiency virus type 1 (HIV-1), specifically 92UG037.8 (clade A) and CZA97.012 (clade C). When the recombinant trimers based on the env genes...

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Detalles Bibliográficos
Publicado en:J Virol
Main Authors: Ringe, Rajesh P., Yasmeen, Anila, Ozorowski, Gabriel, Go, Eden P., Pritchard, Laura K., Guttman, Miklos, Ketas, Thomas A., Cottrell, Christopher A., Wilson, Ian A., Sanders, Rogier W., Cupo, Albert, Crispin, Max, Lee, Kelly K., Desaire, Heather, Ward, Andrew B., Klasse, P. J., Moore, John P.
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology 2015
Assuntos:
Vaccines and Antiviral Agents
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4645310/
https://ncbi.nlm.nih.gov/pubmed/26311893
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01768-15
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