Characterization of the Drug Resistance Profiles of Integrase Strand Transfer Inhibitors in Simian Immunodeficiency Virus SIVmac239

We previously showed that the simian immunodeficiency virus SIVmac239 is susceptible to human immunodeficiency virus (HIV) integrase (IN) strand transfer inhibitors (INSTIs) and that the same IN drug resistance mutations result in similar phenotypes in both viruses. Now we wished to determine whethe...

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Publicado en:J Virol
Autores principales: Hassounah, Said A., Liu, Yannan, Quashie, Peter K., Oliveira, Maureen, Moisi, Daniela, Brenner, Bluma G., Sandstrom, Paul A., Mesplède, Thibault, Wainberg, Mark A.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology 2015
Materias:
Pathogenesis and Immunity
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4645305/
https://ncbi.nlm.nih.gov/pubmed/26378179
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02131-15
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