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A selective delta opioid receptor antagonist based on a stilbene core

Studies of directed ortho metalation reactions on an aromatic substrate with multiple potential directing groups have identified conditions that favor either of two regioisomers. One of these regioisomers has been converted to an analogue of the stilbene pawhuskin A, and been shown to have high sele...

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Publicat a:Bioorg Med Chem Lett
Autors principals: Hartung, Alyssa M., Navarro, Hernan A., Wiemer, David F., Neighbors, Jeffrey D.
Format: Artigo
Idioma:Inglês
Publicat: 2015
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4645280/
https://ncbi.nlm.nih.gov/pubmed/26525865
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmcl.2015.10.059
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