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A selective delta opioid receptor antagonist based on a stilbene core

Studies of directed ortho metalation reactions on an aromatic substrate with multiple potential directing groups have identified conditions that favor either of two regioisomers. One of these regioisomers has been converted to an analogue of the stilbene pawhuskin A, and been shown to have high sele...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Bioorg Med Chem Lett
Main Authors: Hartung, Alyssa M., Navarro, Hernan A., Wiemer, David F., Neighbors, Jeffrey D.
Format: Artigo
Jezik:Inglês
Izdano: 2015
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4645280/
https://ncbi.nlm.nih.gov/pubmed/26525865
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmcl.2015.10.059
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