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A selective delta opioid receptor antagonist based on a stilbene core

Studies of directed ortho metalation reactions on an aromatic substrate with multiple potential directing groups have identified conditions that favor either of two regioisomers. One of these regioisomers has been converted to an analogue of the stilbene pawhuskin A, and been shown to have high sele...

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Detalhes bibliográficos
Publicado no:Bioorg Med Chem Lett
Main Authors: Hartung, Alyssa M., Navarro, Hernan A., Wiemer, David F., Neighbors, Jeffrey D.
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4645280/
https://ncbi.nlm.nih.gov/pubmed/26525865
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmcl.2015.10.059
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