Selective opioid growth factor receptor antagonists based on a stilbene isostere

As part of an ongoing drug development effort aimed at selective opioid receptor ligands based on the pawhuskin natural products we have synthesized a small set of amide isosteres. These amides were centered on lead compounds which are selective antagonists for the delta and kappa opioid receptors....

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Detalhes bibliográficos
Publicado no:Bioorg Med Chem
Main Authors: Stockdale, David P., Titunick, Michelle B., Biegler, Jessica M., Reed, Jessie L., Hartung, Alyssa M., Wiemer, David F., McLaughlin, Patricia J., Neighbors, Jeffrey D.
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5567982/
https://ncbi.nlm.nih.gov/pubmed/28693915
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmc.2017.06.035
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