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Synthesis of Amide Isosteres of Schweinfurthin-based Stilbenes

The schweinfurthins are plant-derived stilbenes with an intriguing profile of anti-cancer activity. To obtain analogues of the schweinfurthins that might preserve the biological activity but have greater water solubility, a formal replacement of the central olefin with an amide has been explored. Tw...

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Bibliografske podrobnosti
izdano v:Bioorg Med Chem
Main Authors: Stockdale, David P., Beutler, John A., Wiemer, David F.
Format: Artigo
Jezik:Inglês
Izdano: 2017
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5763908/
https://ncbi.nlm.nih.gov/pubmed/28866376
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmc.2017.08.016
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