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Glatiramer acetate treatment negatively regulates type I interferon signaling
OBJECTIVE: Glatiramer acetate (GA; Copaxone), a disease-modifying therapy for multiple sclerosis (MS), promotes development of anti-inflammatory (M2, type II) monocytes that can direct differentiation of regulatory T cells. We investigated the innate immune signaling pathways that participate in GA-...
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Publicado no: | Neurol Neuroimmunol Neuroinflamm |
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Main Authors: | , , , , , , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
Lippincott Williams & Wilkins
2015
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4645172/ https://ncbi.nlm.nih.gov/pubmed/26601118 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1212/NXI.0000000000000179 |
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