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Glatiramer Acetate in the Treatment of Multiple Sclerosis: Emerging Concepts Regarding its Mechanism of Action

Glatiramer acetate is a synthetic, random copolymer widely used as a first-line agent for the treatment of relapsing-remitting multiple sclerosis (MS). While earlier studies primarily attributed its clinical effect to a shift in the cytokine secretion of CD4+ T helper (T(h)) cells, growing evidence...

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Hlavní autoři: Lalive, Patrice H., Neuhaus, Oliver, Benkhoucha, Mahdia, Burger, Danielle, Hohlfeld, Reinhard, Zamvil, Scott S., Weber, Martin S.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2011
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3963480/
https://ncbi.nlm.nih.gov/pubmed/21476611
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2165/11588120-000000000-00000
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