Immunomodulatory synergy by combination of atorvastatin and glatiramer acetate in treatment of CNS autoimmunity

One approach to improving efficacy in MS therapy is to identify medications that provide additive or synergistic benefit in combination. Orally administered cholesterol-lowering HMG-CoA reductase inhibitors (known as statins), which exhibit immunomodulatory properties and are effective in treatment...

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Autors principals: Stüve, Olaf, Youssef, Sawsan, Weber, Martin S., Nessler, Stefan, von Büdingen, Hans-Christian, Hemmer, Bernhard, Prod’homme, Thomas, Sobel, Raymond A., Steinman, Lawrence, Zamvil, Scott S.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Clinical Investigation 2006
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1401481/
https://ncbi.nlm.nih.gov/pubmed/16543951
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI25805
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