Immunomodulatory synergy by combination of atorvastatin and glatiramer acetate in treatment of CNS autoimmunity

One approach to improving efficacy in MS therapy is to identify medications that provide additive or synergistic benefit in combination. Orally administered cholesterol-lowering HMG-CoA reductase inhibitors (known as statins), which exhibit immunomodulatory properties and are effective in treatment...

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Main Authors: Stüve, Olaf, Youssef, Sawsan, Weber, Martin S., Nessler, Stefan, von Büdingen, Hans-Christian, Hemmer, Bernhard, Prod’homme, Thomas, Sobel, Raymond A., Steinman, Lawrence, Zamvil, Scott S.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Clinical Investigation 2006
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1401481/
https://ncbi.nlm.nih.gov/pubmed/16543951
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI25805
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