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Hyperpolarized (13)C NMR observation of lactate kinetics in skeletal muscle

The production of glycolytic end products, such as lactate, usually evokes a cellular shift from aerobic to anaerobic ATP generation and O(2) insufficiency. In the classical view, muscle lactate must be exported to the liver for clearance. However, lactate also forms under well-oxygenated conditions...

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Dettagli Bibliografici
Pubblicato in:J Exp Biol
Autori principali: Park, Jae Mo, Josan, Sonal, Mayer, Dirk, Hurd, Ralph E., Chung, Youngran, Bendahan, David, Spielman, Daniel M., Jue, Thomas
Natura: Artigo
Lingua:Inglês
Pubblicazione: The Company of Biologists 2015
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4644943/
https://ncbi.nlm.nih.gov/pubmed/26347554
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jeb.123141
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