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Hyperpolarized (13)C NMR observation of lactate kinetics in skeletal muscle

The production of glycolytic end products, such as lactate, usually evokes a cellular shift from aerobic to anaerobic ATP generation and O(2) insufficiency. In the classical view, muscle lactate must be exported to the liver for clearance. However, lactate also forms under well-oxygenated conditions...

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Detalhes bibliográficos
Publicado no:J Exp Biol
Main Authors: Park, Jae Mo, Josan, Sonal, Mayer, Dirk, Hurd, Ralph E., Chung, Youngran, Bendahan, David, Spielman, Daniel M., Jue, Thomas
Formato: Artigo
Idioma:Inglês
Publicado em: The Company of Biologists 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4644943/
https://ncbi.nlm.nih.gov/pubmed/26347554
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jeb.123141
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