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Hyperpolarized (13)C lactate-to-bicarbonate ratio as a biomarker for monitoring acute response of anti-VEGF treatment

Hyperpolarized [1-(13)C]pyruvate MRS provides a unique imaging opportunity to study reaction kinetics and enzyme activities of in vivo metabolism both because of its favorable imaging characteristics as well as its critical position in the cellular metabolic pathway where it can either be reduced to...

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Détails bibliographiques
Publié dans:NMR Biomed
Auteurs principaux: Park, Jae Mo, Spielman, Daniel M., Josan, Sonal, Jang, Taichang, Merchant, Milton, Hurd, Ralph E., Mayer, Dirk, Recht, Lawrence D.
Format: Artigo
Langue:Inglês
Publié: 2016
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4833516/
https://ncbi.nlm.nih.gov/pubmed/26990457
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/nbm.3509
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