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Hyperpolarized (13)C lactate-to-bicarbonate ratio as a biomarker for monitoring acute response of anti-VEGF treatment

Hyperpolarized [1-(13)C]pyruvate MRS provides a unique imaging opportunity to study reaction kinetics and enzyme activities of in vivo metabolism both because of its favorable imaging characteristics as well as its critical position in the cellular metabolic pathway where it can either be reduced to...

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Detalhes bibliográficos
Publicado no:NMR Biomed
Main Authors: Park, Jae Mo, Spielman, Daniel M., Josan, Sonal, Jang, Taichang, Merchant, Milton, Hurd, Ralph E., Mayer, Dirk, Recht, Lawrence D.
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4833516/
https://ncbi.nlm.nih.gov/pubmed/26990457
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/nbm.3509
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