Volumetric Spiral Chemical Shift Imaging of Hyperpolarized [2-(13)C]Pyruvate in a Rat C6 Glioma Model

PURPOSE: MRS of hyperpolarized [2-(13)C]pyruvate can be used to assess multiple metabolic pathways within mitochondria as the (13)C label is not lost with the conversion of pyruvate to acetyl-CoA. This study presents the first MR spectroscopic imaging of hyperpolarized [2-(13)C]pyruvate in glioma-be...

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Bibliografske podrobnosti
izdano v:Magn Reson Med
Main Authors: Park, Jae Mo, Josan, Sonal, Jang, Taichang, Merchant, Milton, Watkins, Ron, Hurd, Ralph E., Recht, Lawrence D., Mayer, Dirk, Spielman, Daniel M.
Format: Artigo
Jezik:Inglês
Izdano: 2015
Teme:
Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4636489/
https://ncbi.nlm.nih.gov/pubmed/25946547
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/mrm.25766
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