HIV Protease Inhibitors Induce Endoplasmic Reticulum Stress and Disrupt Barrier Integrity in Intestinal Epithelial Cells

BACKGROUND & AIMS: Human immunodeficiency virus (HIV) protease inhibitor (PI)-induced adverse effects have become a serious clinical problem. In addition to their metabolic and cardiovascular complications, these drugs also frequently cause severe gastrointestinal disorders, including mucosal er...

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Veröffentlicht in:Gastroenterology
Hauptverfasser: WU, XUDONG, SUN, LIXIN, ZHA, WEIBIN, STUDER, ELAINE, GURLEY, EMILY, CHEN, LI, WANG, XUAN, HYLEMON, PHILLIP B., PANDAK, WILLIAM M., SANYAL, ARUN J., ZHANG, LUYONG, WANG, GUANGJI, CHEN, JIE, WANG, JIAN–YING, ZHOU, HUIPING
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2009
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4644065/
https://ncbi.nlm.nih.gov/pubmed/19732776
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1053/j.gastro.2009.08.054
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