HIV Protease Inhibitor Lopinavir-induced TNF-a and IL-6 Expression is Coupled to the Unfolded Protein Response and ERK Signaling Pathways in Macrophages

HIV Protease inhibitor (PI)-associated cardiovascular risk, especially atherosclerosis, has become a major concern in the clinic. Macrophages are key players in the inflammatory response and atherosclerosis formation. We have previously shown that HIV PIs induce endoplasmic reticulum (ER) stress, ac...

Πλήρης περιγραφή

Αποθηκεύτηκε σε:
Λεπτομέρειες βιβλιογραφικής εγγραφής
Κύριοι συγγραφείς: Chen, Li, Jarujaron, Sirikalaya, Wu, Xudong, Sun, Lixin, Zha, Weibin, Liang, Guang, Gurley, Emily C., Studer, Elaine J., Hylemon, Phillip B., Pandak, William M., Zhang, Luyong, Wang, Guangji, Li, Xiaokun, Dent, Paul, Zhou, Huiping
Μορφή: Artigo
Γλώσσα:Inglês
Έκδοση: 2009
Θέματα:
Article
Διαθέσιμο Online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2704357/
https://ncbi.nlm.nih.gov/pubmed/19447225
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bcp.2009.03.022
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