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Bile acids regulate hepatic gluconeogenic genes and farnesoid X receptor via Gα(i)-protein-coupled receptors and the AKT pathway

Bile acids are important regulatory molecules that can activate specific nuclear receptors and cell signaling pathways in the liver and gastrointestinal tract. In the current study, the chronic bile fistula (CBF) rat model and primary rat hepatocytes (PRH) were used to study the regulation of glucon...

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Detalhes bibliográficos
Main Authors: Cao, Risheng, Cronk, Zhumei Xu, Zha, Weibin, Sun, Lixin, Wang, Xuan, Fang, Youwen, Studer, Elaine, Zhou, Huiping, Pandak, William M., Dent, Paul, Gil, Gregorio, Hylemon, Phillip B.
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Biochemistry and Molecular Biology 2010
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2903791/
https://ncbi.nlm.nih.gov/pubmed/20305288
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1194/jlr.M004929
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