Activation of Bile Acid Biosynthesis by the p38 Mitogen-activated Protein Kinase (MAPK): HEPATOCYTE NUCLEAR FACTOR-4α PHOSPHORYLATION BY THE p38 MAPK IS REQUIRED FOR CHOLESTEROL 7α-HYDROXYLASE EXPRESSION()

Bile acids are required for intestinal absorption and biliary solubilization of cholesterol and lipids. In addition, bile acids play a crucial role in cholesterol homeostasis. One of the key enzymes in the bile acid biosynthetic pathways is cholesterol 7α-hydroxylase/cytochrome P450 7α-hydroxylase (...

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Библиографические подробности
Главные авторы: Xu, Zhumei, Tavares-Sanchez, Olga L., Li, Quanzhong, Fernando, Josephine, Rodriguez, Carmen M., Studer, Elaine J., Pandak, William M., Hylemon, Phillip B., Gil, Gregorio
Формат: Artigo
Язык:Inglês
Опубликовано: 2007
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Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3291957/
https://ncbi.nlm.nih.gov/pubmed/17603092
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M611481200
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