Prevention of HIV Protease Inhibitor-Induced Dysregulation of Hepatic Lipid Metabolism by Raltegravir via Endoplasmic Reticulum Stress Signaling Pathways

Hyperlipidemia associated with the HIV protease inhibitor (PI), the major component of highly active antiretroviral treatment (HAART) for HIV infection, has stimulated interest in developing new agents that minimize these side effects in the clinic. HIV integrase inhibitor is a new class of anti-HIV...

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Detalhes bibliográficos
Main Authors: Cao, Risheng, Hu, Yiqiao, Wang, Yun, Gurley, Emily C., Studer, Elaine J., Wang, Xuan, Hylemon, Phillip B., Pandak, William M., Sanyal, Arun J., Zhang, Luyong, Zhou, Huiping
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Pharmacology and Experimental Therapeutics 2010
Assuntos:
Gastrointestinal, Hepatic, Pulmonary, and Renal
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2913777/
https://ncbi.nlm.nih.gov/pubmed/20472667
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/jpet.110.168484
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