The Divergent CD8(+) T Cell Adjuvant Properties of LT-IIb and LT-IIc, Two Type II Heat-Labile Enterotoxins, Are Conferred by Their Ganglioside-Binding B Subunits

Poor immune responses elicited by vaccine antigens can be enhanced by the use of appropriate adjuvants. Type II heat-labile enterotoxins (HLT) produced by Escherichia coli are extremely potent adjuvants that augment both humoral and cellular immunity to co-administered antigens. Recent findings demo...

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Vydáno v:PLoS One
Hlavní autoři: Hu, John C., Greene, Christopher J., King-Lyons, Natalie D., Connell, Terry D.
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2015
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4643920/
https://ncbi.nlm.nih.gov/pubmed/26565800
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0142942
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