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Cholera toxin, LT-I, LT-IIa, and LT-IIb: the critical role of ganglioside-binding in immunomodulation by Type I and Type II heat-labile enterotoxins
The heat-labile enterotoxins (HLT) expressed by Vibrio cholerae (cholera toxin) and Escherichia coli (LT-I, LT-IIa, and LT-IIb) are potent systemic and mucosal adjuvants. Co-administration of the enterotoxins with a foreign antigen (Ag) produces an augmented immune response to that antigen. Although...
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| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
2007
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| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2849181/ https://ncbi.nlm.nih.gov/pubmed/17931161 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1586/14760584.6.5.821 |
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