Intradermal Administration of the Type II Heat-Labile Enterotoxins LT-IIb and LT-IIc of Enterotoxigenic Escherichia coli Enhances Humoral and CD8(+) T Cell Immunity to a Co-Administered Antigen

Vaccinations are extremely effective at combating infectious diseases. Many conserved antigen (Ag) targets, however, are poorly immunogenic. Protein subunit vaccines frequently elicit only humoral immune responses and fail to confer protection against serious intracellular pathogens. These barriers...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Hu, John C., Mathias-Santos, Camila, Greene, Christopher J., King-Lyons, Natalie D., Rodrigues, Juliana F., Hajishengallis, George, Ferreira, Luís C. S., Connell, Terry D.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4275187/
https://ncbi.nlm.nih.gov/pubmed/25536061
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0113978
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