Gene-based meta-analysis of genome-wide association studies implicates new loci involved in obesity

To date, genome-wide association studies (GWASs) have identified >100 loci with single variants associated with body mass index (BMI). This approach may miss loci with high allelic heterogeneity; therefore, the aim of the present study was to use gene-based meta-analysis to identify regions with...

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Библиографические подробности
Опубликовано в: :Hum Mol Genet
Главные авторы: Hägg, Sara, Ganna, Andrea, Van Der Laan, Sander W., Esko, Tonu, Pers, Tune H., Locke, Adam E., Berndt, Sonja I., Justice, Anne E., Kahali, Bratati, Siemelink, Marten A., Pasterkamp, Gerard, Strachan, David P., Speliotes, Elizabeth K., North, Kari E., Loos, Ruth J.F., Hirschhorn, Joel N., Pawitan, Yudi, Ingelsson, Erik
Формат: Artigo
Язык:Inglês
Опубликовано: Oxford University Press 2015
Предметы:
Association Studies Articles
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4643645/
https://ncbi.nlm.nih.gov/pubmed/26376864
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddv379
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