Gene-based meta-analysis of genome-wide association studies implicates new loci involved in obesity

To date, genome-wide association studies (GWASs) have identified >100 loci with single variants associated with body mass index (BMI). This approach may miss loci with high allelic heterogeneity; therefore, the aim of the present study was to use gene-based meta-analysis to identify regions with...

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Sparad:
Bibliografiska uppgifter
I publikationen:Hum Mol Genet
Huvudupphovsmän: Hägg, Sara, Ganna, Andrea, Van Der Laan, Sander W., Esko, Tonu, Pers, Tune H., Locke, Adam E., Berndt, Sonja I., Justice, Anne E., Kahali, Bratati, Siemelink, Marten A., Pasterkamp, Gerard, Strachan, David P., Speliotes, Elizabeth K., North, Kari E., Loos, Ruth J.F., Hirschhorn, Joel N., Pawitan, Yudi, Ingelsson, Erik
Materialtyp: Artigo
Språk:Inglês
Publicerad: Oxford University Press 2015
Ämnen:
Association Studies Articles
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4643645/
https://ncbi.nlm.nih.gov/pubmed/26376864
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddv379
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