Gene-based meta-analysis of genome-wide association studies implicates new loci involved in obesity

To date, genome-wide association studies (GWASs) have identified >100 loci with single variants associated with body mass index (BMI). This approach may miss loci with high allelic heterogeneity; therefore, the aim of the present study was to use gene-based meta-analysis to identify regions with...

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Detalhes bibliográficos
Publicado no:Hum Mol Genet
Main Authors: Hägg, Sara, Ganna, Andrea, Van Der Laan, Sander W., Esko, Tonu, Pers, Tune H., Locke, Adam E., Berndt, Sonja I., Justice, Anne E., Kahali, Bratati, Siemelink, Marten A., Pasterkamp, Gerard, Strachan, David P., Speliotes, Elizabeth K., North, Kari E., Loos, Ruth J.F., Hirschhorn, Joel N., Pawitan, Yudi, Ingelsson, Erik
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2015
Assuntos:
Association Studies Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4643645/
https://ncbi.nlm.nih.gov/pubmed/26376864
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddv379
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