Gene-based meta-analysis of genome-wide association studies implicates new loci involved in obesity

To date, genome-wide association studies (GWASs) have identified >100 loci with single variants associated with body mass index (BMI). This approach may miss loci with high allelic heterogeneity; therefore, the aim of the present study was to use gene-based meta-analysis to identify regions with...

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發表在:Hum Mol Genet
Main Authors: Hägg, Sara, Ganna, Andrea, Van Der Laan, Sander W., Esko, Tonu, Pers, Tune H., Locke, Adam E., Berndt, Sonja I., Justice, Anne E., Kahali, Bratati, Siemelink, Marten A., Pasterkamp, Gerard, Strachan, David P., Speliotes, Elizabeth K., North, Kari E., Loos, Ruth J.F., Hirschhorn, Joel N., Pawitan, Yudi, Ingelsson, Erik
格式: Artigo
語言:Inglês
出版: Oxford University Press 2015
主題:
Association Studies Articles
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC4643645/
https://ncbi.nlm.nih.gov/pubmed/26376864
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddv379
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