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Meta-analysis of Gene-Level Associations for Rare Variants Based on Single-Variant Statistics

Meta-analysis of genome-wide association studies (GWASs) has led to the discoveries of many common variants associated with complex human diseases. There is a growing recognition that identifying “causal” rare variants also requires large-scale meta-analysis. The fact that association tests with rar...

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Détails bibliographiques
Auteurs principaux: Hu, Yi-Juan, Berndt, Sonja I., Gustafsson, Stefan, Ganna, Andrea, Hirschhorn, Joel, North, Kari E., Ingelsson, Erik, Lin, Dan-Yu
Format: Artigo
Langue:Inglês
Publié: Elsevier 2013
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3738834/
https://ncbi.nlm.nih.gov/pubmed/23891470
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajhg.2013.06.011
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