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Determinants of ligand binding and catalytic activity in the myelin enzyme 2′,3′-cyclic nucleotide 3′-phosphodiesterase

2′,3′-cyclic nucleotide 3′-phosphodiesterase (CNPase) is an enzyme highly abundant in the central nervous system myelin of terrestrial vertebrates. The catalytic domain of CNPase belongs to the 2H phosphoesterase superfamily and catalyzes the hydrolysis of nucleoside 2′,3′-cyclic monophosphates to n...

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Dades bibliogràfiques
Publicat a:Sci Rep
Autors principals: Raasakka, Arne, Myllykoski, Matti, Laulumaa, Saara, Lehtimäki, Mari, Härtlein, Michael, Moulin, Martine, Kursula, Inari, Kursula, Petri
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 2015
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4643303/
https://ncbi.nlm.nih.gov/pubmed/26563764
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep16520
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