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Determinants of ligand binding and catalytic activity in the myelin enzyme 2′,3′-cyclic nucleotide 3′-phosphodiesterase

2′,3′-cyclic nucleotide 3′-phosphodiesterase (CNPase) is an enzyme highly abundant in the central nervous system myelin of terrestrial vertebrates. The catalytic domain of CNPase belongs to the 2H phosphoesterase superfamily and catalyzes the hydrolysis of nucleoside 2′,3′-cyclic monophosphates to n...

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Detalles Bibliográficos
Publicado en:Sci Rep
Main Authors: Raasakka, Arne, Myllykoski, Matti, Laulumaa, Saara, Lehtimäki, Mari, Härtlein, Michael, Moulin, Martine, Kursula, Inari, Kursula, Petri
Formato: Artigo
Idioma:Inglês
Publicado: Nature Publishing Group 2015
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4643303/
https://ncbi.nlm.nih.gov/pubmed/26563764
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep16520
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