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Crystallographic Analysis of the Reaction Cycle of 2′,3′-Cyclic Nucleotide 3′-Phosphodiesterase, a Unique Member of the 2H Phosphoesterase Family

2H phosphoesterases catalyze reactions on nucleotide substrates and contain two conserved histidine residues in the active site. Very limited information is currently available on the details of the active site and substrate/product binding during the catalytic cycle of these enzymes. We performed a...

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Detalhes bibliográficos
Publicado no:J Mol Biol
Main Authors: Myllykoski, Matti, Raasakka, Arne, Lehtimäki, Mari, Han, Huijong, Kursula, Inari, Kursula, Petri
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier Ltd. 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7094350/
https://ncbi.nlm.nih.gov/pubmed/23831225
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2013.06.012
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