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Determinants of ligand binding and catalytic activity in the myelin enzyme 2′,3′-cyclic nucleotide 3′-phosphodiesterase

2′,3′-cyclic nucleotide 3′-phosphodiesterase (CNPase) is an enzyme highly abundant in the central nervous system myelin of terrestrial vertebrates. The catalytic domain of CNPase belongs to the 2H phosphoesterase superfamily and catalyzes the hydrolysis of nucleoside 2′,3′-cyclic monophosphates to n...

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Bibliografiske detaljer
Udgivet i:Sci Rep
Main Authors: Raasakka, Arne, Myllykoski, Matti, Laulumaa, Saara, Lehtimäki, Mari, Härtlein, Michael, Moulin, Martine, Kursula, Inari, Kursula, Petri
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2015
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4643303/
https://ncbi.nlm.nih.gov/pubmed/26563764
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep16520
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