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In vitro mechanism for down-regulation of ERalpha expression by epigallocatechin gallate in ER+/PR+ human breast cancer cells

SCOPE: Exposure of the breast to estrogens and other sex hormones is an important cancer risk factor and estrogen receptor down-regulators are attracting significant clinical interest. Epigallocatechin gallate (EGCG), a polyphenolic compound found in green tea, has gained considerable attention for...

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Bibliographische Detailangaben
Veröffentlicht in:Mol Nutr Food Res
Hauptverfasser: De Amicis, Francesca, Russo, Alessandra, Avena, Paola, Santoro, Marta, Vivacqua, Adele, Bonofiglio, Daniela, Mauro, Loredana, Aquila, Saveria, Tramontano, Donatella, Fuqua, Suzanne AW, Andò, Sebastiano
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2013
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4642730/
https://ncbi.nlm.nih.gov/pubmed/23322423
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/mnfr.201200560
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