Resveratrol, through NF-Y/p53/Sin3/HDAC1 complex phosphorylation, inhibits estrogen receptor α gene expression via p38(MAPK)/CK2 signaling in human breast cancer cells

Agents to counteract acquired resistance to hormonal therapy for breast cancer would substantially enhance the long-term benefits of hormonal therapy. In the present study, we demonstrate how resveratrol (Res) inhibits human breast cancer cell proliferation, including MCF-7 tamoxifen-resistant cells...

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Detalhes bibliográficos
Principais autores: De Amicis, Francesca, Giordano, Francesca, Vivacqua, Adele, Pellegrino, Michele, Panno, Maria Luisa, Tramontano, Donatella, Fuqua, Suzanne A. W., Andò, Sebastiano
Formato: Artigo
Idioma:Inglês
Publicado em: Federation of American Societies for Experimental Biology 2011
Assuntos:
Research Communications
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3177579/
https://ncbi.nlm.nih.gov/pubmed/21737614
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.10-178871
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