Bergapten induces proteasome-dependent degradation of ER in breast cancer cells: Involvement of SMAD4 in the ubiquitination process

INTRODUCTION: ERα function is crucial for development of normal mammary gland as well as in the process of progression of breast cancer cells. Signals that target receptor levels contribute to regulate estrogens effects in the cells. An intricate cross-regulation has been documented between ERα and...

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Vydáno v:Breast Cancer Res Treat
Hlavní autoři: Panno, M.L., Giordano, F., Rizza, P., Pellegrino, M., Zito, M., Giordano, C., Mauro, L., Catalano, S., Aquila, A., Sisci, D., De Amicis, F., Vivacqua, A., Fuqua, S.W.A., Andò, S.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2012
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4482105/
https://ncbi.nlm.nih.gov/pubmed/23053665
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10549-012-2282-3
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