Activation of TGF-β1-CD147 positive feedback loop in hepatic stellate cells promotes liver fibrosis

Activation of hepatic stellate cells (HSCs) by transforming growth factor-β1 (TGF-β1) initiates HBV-associated fibrogenesis. The mechanism of TGF-β1 modulating HSC activation is not fully uncovered. We hypothesized a positive feedback signaling loop of TGF-β1-CD147 promoting liver fibrogenesis by ac...

Ful tanımlama

Kaydedildi:
Detaylı Bibliyografya
Yayımlandı:Sci Rep
Asıl Yazarlar: Li, Hai-Yan, Ju, Di, Zhang, Da-Wei, Li, Hao, Kong, Ling-Min, Guo, Yanhai, Li, Can, Wang, Xi-Long, Chen, Zhi-Nan, Bian, Huijie
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Nature Publishing Group 2015
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4642271/
https://ncbi.nlm.nih.gov/pubmed/26559755
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep16552
Etiketler: Etiketle
Etiket eklenmemiş, İlk siz ekleyin!

Benzer Materyaller