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SIRT6 Deficiency Culminates in Low-Turnover Osteopenia
Deficiency of Sirtuin 6 (SIRT6), a chromatin-related deacetylase, in mice reveals severe premature aging phenotypes including osteopenia. However, the underlying molecular mechanisms of SIRT6 in bone metabolism are unknown. Here we show that SIRT6 deficiency in mice produces low-turnover osteopenia...
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| Publicado no: | Bone |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4640951/ https://ncbi.nlm.nih.gov/pubmed/26189760 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bone.2015.07.018 |
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