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Ligand trap for the Activin Type IIA receptor protects against vascular disease and renal fibrosis in mice with chronic kidney disease

The causes of cardiovascular mortality associated with chronic kidney disease (CKD) are partly attributed to the CKD-mineral bone disorder (CKD-MBD). The causes of the early CKD-MBD are not well known. Our discovery of Wnt (portmanteau of wingless and int) inhibitors, especially Dickkopf 1, produced...

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Bibliografske podrobnosti
izdano v:Kidney Int
Main Authors: Agapova, Olga A., Fang, Yifu, Sugatani, Toshifumi, Seifert, Michael E., Hruska, Keith A.
Format: Artigo
Jezik:Inglês
Izdano: 2016
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4868771/
https://ncbi.nlm.nih.gov/pubmed/27165838
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.kint.2016.02.002
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