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Ligand trap for the Activin Type IIA receptor protects against vascular disease and renal fibrosis in mice with chronic kidney disease

The causes of cardiovascular mortality associated with chronic kidney disease (CKD) are partly attributed to the CKD-mineral bone disorder (CKD-MBD). The causes of the early CKD-MBD are not well known. Our discovery of Wnt (portmanteau of wingless and int) inhibitors, especially Dickkopf 1, produced...

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Detalhes bibliográficos
Publicado no:Kidney Int
Main Authors: Agapova, Olga A., Fang, Yifu, Sugatani, Toshifumi, Seifert, Michael E., Hruska, Keith A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4868771/
https://ncbi.nlm.nih.gov/pubmed/27165838
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.kint.2016.02.002
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