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Selective Runx2-II deficiency leads to low-turnover osteopenia in adult mice
Runx2 transcribes Runx2-II and Runx2-I isoforms with distinct N-termini. Deletion of both isoforms results in complete arrest of bone development, whereas selective loss of Runx2-II is sufficient to form a grossly intact skeleton with impaired endochondral bone development. To elucidate the role of...
Gorde:
| Egile Nagusiak: | , , , , , , , |
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| Formatua: | Artigo |
| Hizkuntza: | Inglês |
| Argitaratua: |
2005
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| Gaiak: | |
| Sarrera elektronikoa: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1360182/ https://ncbi.nlm.nih.gov/pubmed/15936013 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ydbio.2005.04.028 |
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