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Polycystin-1 Regulates Skeletogenesis through Stimulation of the Osteoblast-specific Transcription Factor RUNX2-II

Polycystin-1 (PC1) may play an important role in skeletogenesis through regulation of the bone-specific transcription factor Runx2-II. In the current study we found that PC1 co-localizes with the calcium channel polycystin-2 (PC2) in primary cilia of MC3T3-E1 osteoblasts. To establish the role of Ru...

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Autors principals: Xiao, Zhousheng, Zhang, Shiqin, Magenheimer, Brenda S., Luo, Junming, Quarles, L. Darryl
Format: Artigo
Idioma:Inglês
Publicat: American Society for Biochemistry and Molecular Biology 2008
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2335361/
https://ncbi.nlm.nih.gov/pubmed/18321855
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M710407200
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