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RNA-sequencing reveals transcriptional up-regulation of Trem2 in response to bexarotene treatment
We have recently demonstrated that short term bexarotene treatment of APP/PS1 mice significantly improves their cognitive performance. While there were no changes in plaque load, or insoluble Aβ levels in brain, biochemical analysis strongly suggested improved clearance of soluble Aβ, including Aβ o...
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| Gepubliceerd in: | Neurobiol Dis |
|---|---|
| Hoofdauteurs: | , , , , , |
| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
2015
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| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4640940/ https://ncbi.nlm.nih.gov/pubmed/26071899 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.nbd.2015.05.019 |
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