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Dystrophin–glycoprotein complex regulates muscle nitric oxide production through mechanoregulation of AMPK signaling
Patients deficient in dystrophin, a protein that links the cytoskeleton to the extracellular matrix via the dystrophin–glycoprotein complex (DGC), exhibit muscular dystrophy, cardiomyopathy, and impaired muscle nitric oxide (NO) production. We used live-cell NO imaging and in vitro cyclic stretch of...
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| Publicat a: | Proc Natl Acad Sci U S A |
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| Autors principals: | , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
National Academy of Sciences
2015
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4640723/ https://ncbi.nlm.nih.gov/pubmed/26483453 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1512991112 |
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